Protein name:
Very low-density lipoprotein receptor (VLDL receptor;VLDL-R) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds to the extracellular matrix protein Reelin. Interacts with DAB1. Interacts with VLDLR. Interacts with SNX17.
Function:
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Membrane
clathrin-coated pit
Single-pass type I membrane protein
Protein Attributes:
50:
MGTSARWALW | LLLALCWAPR | DSGATASGKK | AKCDSSQFQC | TNGRCITLLW |
100:
KCDGDEDCAD | GSDEKNCVKK | TCAESDFVCK | NGQCVPNRWQ | CDGDPDCEDG |
150:
SDESPEQCHM | RTCRINEISC | GARSTQCIPV | SWRCDGENDC | DNGEDEENCG |
200:
NITCSADEFT | CSSGRCVSRN | FVCNGQDDCD | DGSDELDCAP | PTCGAHEFQC |
250:
STSSCIPLSW | VCDDDADCSD | QSDESLEQCG | RQPVIHTKCP | TSEIQCGSGE |
300:
CIHKKWRCDG | DPDCKDGSDE | VNCPSRTCRP | DQFECEDGSC | IHGSRQCNGI |
350:
RDCVDGSDEV | NCKNVNQCLG | PGKFKCRSGE | CIDMSKVCDQ | EQDCRDWSDE |
400:
PLKECHINEC | LVNNGGCSHI | CKDLVIGYEC | DCAAGFELID | RKTCGDIDEC |
450:
QNPGICSQIC | INLKGGYKCE | CSRGYQMDLA | TGVCKAVGKE | PSLIFTNRRD |
500:
IRKIGLERKE | YIQLVEQLRN | TVALDADIAA | QKLFWADLSQ | KAIFSASIDD |
550:
KVGRHFKMID | NVYNPAAIAV | DWVYKTIYWT | DAASKTISVA | TLDGAKRKFL |
600:
FNSDLREPAS | IAVDPLSGFV | YWSDWGEPAK | IEKAGMNGFD | RRPLVTEDIQ |
650:
WPNGITLDLV | KSRLYWLDSK | LHMLSSVDLN | GQDRRIVLKS | LEFLAHPLAL |
700:
TIFEDRVYWI | DGENEAVYGA | NKFTGSELAT | LVNNLNDAQD | IIVYHELVQP |
750:
SGKNWCEDDM | ENGGCEYLCL | PAPQINDHSP | KYTCSCPNGY | NLEENGRECQ |
800:
STSTPVTYSE | TKDINTTDIL | RTSGLVPGGI | NVTTAVSEVS | VPPKGTSAAW |
850:
AILPLLLLVM | AAVGGYLMWR | NWQHKNMKSM | NFDNPVYLKT | TEEDLSIDIG |
873:
RHSASVGHTY | PAISVVSTDD | DLA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Rabbit
Chicken
ELISA Kit for Mouse VLDL receptor
ELISA Kit for Mouse VLDL receptor
ELISA Kit for Mouse VLDL receptor
ELISA Kit for Mouse VLDL receptor
ELISA Kit for Mouse VLDL receptor
CLIA Kit for Mouse VLDL receptor
CLIA Kit for Mouse VLDL receptor
CLIA Kit for Mouse VLDL receptor
CLIA Kit for Mouse VLDL receptor
CLIA Kit for Mouse VLDL receptor
Polyclonal Antibody for Mouse VLDL receptor
Polyclonal Antibody for Mouse VLDL receptor
Polyclonal Antibody for Mouse VLDL receptor
Polyclonal Antibody for Mouse VLDL receptor
Polyclonal Antibody for Mouse VLDL receptor
Monoclonal Antibody for Mouse VLDL receptor
Monoclonal Antibody for Mouse VLDL receptor
Monoclonal Antibody for Mouse VLDL receptor
Monoclonal Antibody for Mouse VLDL receptor
Monoclonal Antibody for Mouse VLDL receptor
Protein for Mouse VLDL receptor
Protein for Mouse VLDL receptor
Protein for Mouse VLDL receptor
Protein for Mouse VLDL receptor
Protein for Mouse VLDL receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
tissue :
Heart .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Skeletal muscle .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 204-262
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH REELIN
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SNX17
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LDLRAP1
7.
"The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2."
Hong C.
,
Duit S.
,
Jalonen P.
,
Out R.
,
Scheer L.
,
Sorrentino V.
,
Boyadjian R.
,
Rodenburg K.W.
,
Foley E.
,
Korhonen L.
,
Lindholm D.
,
Nimpf J.
,
van Berkel T.J.
,
Tontonoz P.
,
Zelcer N.
J. Biol. Chem.285:19720-19726(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION